{"id":4656,"date":"2018-08-15T16:57:57","date_gmt":"2018-08-15T16:57:57","guid":{"rendered":"http:\/\/koval-olena.com\/?page_id=4656\/"},"modified":"2022-08-12T16:32:14","modified_gmt":"2022-08-12T16:32:14","slug":"regenerative-medicine","status":"publish","type":"page","link":"https:\/\/koval-olena.com\/en\/services\/regenerative-medicine\/","title":{"rendered":"Regenerative Medicine"},"content":{"rendered":"

[vc_row css=”.vc_custom_1521710301609{margin-top: 30px !important;}”][vc_column][vc_column_text]Regenerative medicine\u00a0<\/strong><\/span>is a general term for various therapeutic and surgical cellular technologies (organ regeneration and tissue engineering<\/strong>)\u00a0aimed at partial or complete compensation of the functions of damaged or lost tissues (organs).

Read more<\/a>
<\/p>\n

There are two main directions in the regenerative medicine.<\/p>\n

One of them – regenerative cellular<\/strong> (or simply cellular) therapy<\/strong> is associated with stimulation of cell-based tissue regeneration by transplantation of stem cells or their associates with somatic cells.<\/p>\n

The second direction is to restore the integrity and functions of tissues and organs with the help of so-called biomaterial-based tissue regeneration<\/strong> (TIC), which includes the following components:<\/p>\n

1) cells capable of forming a functioning extracellular matrix;<\/p>\n

2) a suitable biodegradable carrier (matrix) for cell transplantation;<\/p>\n

3) bioactive molecules (cytokines, growth factors) that exert a biostimulating effect on the cells of the damaged tissue.<\/p>\n

As a cellular component, cells of various types and different origins are used, including embryonic progenitor cells (progenitor cells), multipotent mesenchymal stem cells (MMSC), and differentiated (specialized, tissue-specific) cells.<\/p>\n

Autologous or allogeneic differentiated cells are obtained by biopsy, cultured in vitro and transplanted to the site of injury.<\/p>\n

Technologies of tissue and regenerative medicine<\/strong> can be divided into three groups:<\/p>\n

– Biostimulation of regeneration of patient tissues with the help of bioactive materials;<\/p>\n

– Cell therapy – the use of stem cells or signal biomolecules to stimulate the processes of tissue regeneration;<\/p>\n

– Tissue engineering – tissue-engineering structures of organs and tissues. <\/div><\/div>[\/vc_column_text][\/vc_column][\/vc_row][vc_row css=”.vc_custom_1521709592767{margin-top: 30px !important;}”][vc_column][vc_tta_tabs style=”flat” color=”white” active_section=”1″][vc_tta_section title=”FAT & PRP Regen Lab” tab_id=”1521106419927-3466537e-d22f”][vc_column_text]\"\"Regenerative Cell Therapy<\/span><\/strong><\/p>\n

 <\/p>\n

Fat grafting<\/span><\/strong><\/a> (lipostructure, lipofilling, lipomodeling) is the optimal method for filling soft tissues (restoring volumes, filling in minus defects), because adipose tissue is the source of mesenchymal stem cells <\/strong>(MMSC<\/strong>) from which new healthy tissue is synthesized.<\/p>\n

\"\"<\/p>\n

To improve the survival rate of adipocytes, lipoaspirate is mixed with platelet-rich plasma<\/strong> (PRP<\/strong>), which is a reservoir of growth factors<\/strong> (PDGF, TGF, IGF, EGF, VEGF, FGF). These growth factors provide neoangiogenesis and revascularization of the fat graft (formation of new vessels and restoration of blood circulation), which makes it possible to predict the survival of adipose tissue and guarantees a long-term result.[\/vc_column_text][vc_column_text]\"\" Nanofat<\/span><\/strong><\/p>\n

In addition to the classic procedure of fat grafting (restoration of tissue volumes), modern technologies make it possible to obtain an innovative product – Nanofat<\/strong>, which with the help of mesenchymal stem cells (MMSC<\/strong>) allows to achieve a high-quality and long-term result of the rejuvenation of delicate and thin tissues<\/strong> (without creating additional volume) of the periorbital zone, hands and neck and d\u00e9collet\u00e9.<\/p>\n

This technique (Nanofat & MMSC<\/strong>) is also successfully used to restore<\/strong> the integrity of damaged joint tissue and muscular-ligamentous apparatus<\/strong> in traumatic and degenerative processes, as well as for the treatment of scars<\/strong>.[\/vc_column_text][\/vc_tta_section][vc_tta_section title=”Joints treatment” tab_id=”1521106447028-1033e984-48d3″][vc_column_text]\"\"<\/a><\/p>\n

For joints treatment<\/strong> at the TRIEN Medical Center we are used the intra-articular injections of PRP<\/strong> (platelet-rich plasma), Hyaluronic acid<\/strong>, MMSC<\/strong> (own mesenchymal stem cells) and injections of homotoxicological drugs (Heel<\/strong>), as well as a combination of these methods.\u00a0Ultrasonic control can be used if necessary.<\/p>\n

“Joint physiopathology may be caused by mechanical diseases, inflammatory or neuropathic diseases.”<\/strong><\/em><\/p>\n

It has been clinically proven that PRP<\/strong> acts as an autologous (self) analgesic and anti-inflammatory agent<\/strong> in pathological processes in the joints. PRP is an effective alternative treatment for corticosteroids (especially for patients with diabetes mellitus), since PRP is not, in contrast to hormones, harmful in the long term “(data from clinical studies RegeLab, Switzerland<\/a>).<\/p>\n

\"\"<\/p>\n

As the major component of the synovial fluid, hyaluronic acid<\/strong> assumes an important role in the viscoelastic properties of the articular cartilage, improving absorption of shocks, as well as lubrication of the joints.<\/p>\n

Osteoarthritis<\/strong> is characterized by both a decrease in the concentration of hyaluronic acid and a reduction of its molecular weight, which may lead to an increase of pain and a loss of joint functions.<\/p>\n

Today one of the most widely used therapeutic approaches in the treatment of osteoarthritis symptoms are Intra-articular injections of Hyaluronic acid<\/strong>.<\/p>\n

“The uniqueness and high therapeutic effect of the procedure is to restore the concentration of Hyaluronic acid<\/strong> and its molecular mass in the joints<\/strong>; the effect of the procedure is immediate, joint pain is greatly reduced and its mobility is improved.<\/p>\n

The clinical benefits of intra-articular injections of Hyaluronic acid have been proven by long-term positive results<\/strong>\u00a0“(data from clinical studies RegeLab, Switzerland).[\/vc_column_text][\/vc_tta_section][vc_tta_section title=”Sports injuries” tab_id=”1521106419986-31579328-22d9″][vc_column_text]\"\"<\/a><\/p>\n

Sports injuries<\/strong> are often accompanied by the development of conditions such as osteoarthritis, chondropathy and tendinopathy<\/strong>.<\/p>\n

A highly effective solution to accelerate the healing of tendon and muscle injuries and to treat osteoarthritis (with minimal risk for the patient!) is PRP therapy<\/strong><\/a>.<\/p>\n

The philosophy of this therapy is to combine advanced technologies with the body\u2019s natural ability to heal.<\/strong><\/em><\/p>\n

Depending on the individual condition of the patient, it may take from 1 to 3 injections of PRP<\/strong> within 1-2 months.<\/p>\n

 <\/p>\n

“Clinical studies date have shown that PRP treatment<\/strong> resulted in improved functional results and reduced pain in patients with an early stage of the disease of osteoarthritis<\/strong> of the knee, hip and shoulder.<\/p>\n

PRP injection<\/strong> significantly improved the clinical outcome over time at the patients with chondropathy<\/strong> of the knee, hip, ankle, and shoulder.<\/p>\n

In tendinopathies<\/strong>, PRP treatment<\/strong> has provided significant clinical benefits in 90% of patients with continuous improvement over time and with a low recurrence rate.<\/p>\n

The study showed a significant analgesic effect of therapy, even if patients received only one injection of PRP “(data from clinical studies RegenLab, Switzerland<\/a>).[\/vc_column_text][\/vc_tta_section][vc_tta_section title=”Scar treatment” tab_id=”1522357627173-7d85b172-85ee” el_class=”\u043b\u0435\u0447\u0435\u043d\u0438\u0435 “][vc_column_text]\"\"<\/b>Scar<\/strong> is a dense connective tissue formation that has arisen as a result of tissue regeneration after surgery, injury or inflammation.<\/p>\n

To restore normal tissue in the area of \u200b\u200bthe scar<\/strong>, modern technologies of laser medicine<\/strong>,\u00a0tissue and regenerative medicine<\/strong> and reconstructive s<\/strong>urgery<\/strong> <\/a>are used.<\/p>\n

The optimal method for its correction is determined depending on the type of scar, its localization, the duration of scar formation and the characteristics of surrounding tissues, *.<\/p>\n

The combination of advanced techniques of regenerative medicine (PRP<\/strong>, MMSC<\/strong>) and, if necessary, reconstructive surgery allows you to fully restore normal tissue<\/strong> or bring the correction of the scar to the maximum aesthetic result<\/strong>.<\/p>\n

* Consultations on the correction of scars are carried out without payment.[\/vc_column_text][\/vc_tta_section][\/vc_tta_tabs][\/vc_column][\/vc_row][vc_row][vc_column width=”1\/4″][vc_separator][\/vc_column][vc_column width=”3\/4″][\/vc_column][\/vc_row][vc_row][vc_column][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"

[vc_row css=”.vc_custom_1521710301609{margin-top: 30px !important;}”][vc_column][vc_column_text]Regenerative medicine\u00a0is a general term for various therapeutic and surgical cellular technologies (organ regeneration and tissue engineering)\u00a0aimed at partial or complete compensation of […]<\/p>\n","protected":false},"author":4,"featured_media":0,"parent":4565,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/koval-olena.com\/en\/wp-json\/wp\/v2\/pages\/4656"}],"collection":[{"href":"https:\/\/koval-olena.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/koval-olena.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/koval-olena.com\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/koval-olena.com\/en\/wp-json\/wp\/v2\/comments?post=4656"}],"version-history":[{"count":1,"href":"https:\/\/koval-olena.com\/en\/wp-json\/wp\/v2\/pages\/4656\/revisions"}],"predecessor-version":[{"id":8302,"href":"https:\/\/koval-olena.com\/en\/wp-json\/wp\/v2\/pages\/4656\/revisions\/8302"}],"up":[{"embeddable":true,"href":"https:\/\/koval-olena.com\/en\/wp-json\/wp\/v2\/pages\/4565"}],"wp:attachment":[{"href":"https:\/\/koval-olena.com\/en\/wp-json\/wp\/v2\/media?parent=4656"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}